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10.3390/bioengineering10010064
When using dilute acetic acid (0.1% v/v) as a solvent, it can improve initial solubilization of certain peptide batches, but the solution pH should be adjusted to near-physiological range before administration to avoid tissue irritation at the injection site in animal models
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Moreover, integrating host transcriptomic data with gut microbiome profiles obtained by QIIME has uncovered genes and pathways related to inflammation, gut barrier protection, and energy metabolism [108]
