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Other studies had significant results, but typically by using tremendous amounts of supplements and/or combining oral supplements with injections or transdermal skin patches (21, 22)

Because of B12's importance, many people choose to supplement it

The choice of SH-SY5Y cells was guided by their status as a permanently established neuronal cell line, valued for their human origin, possession of catecholaminergic neuronal properties, and ease of maintenance 38

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To offset the damage, helper cells seal off the damaged area by creating blockades of protein that help prevent the spread of bacteria and toxins to the surrounding areas