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Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation

10.1016/j.phyplu.2020.100014 41 El-ShehawiA

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Nonetheless, treatment with miR-34a agomir decreased the levels of SIRT1 and members of the Wnt/-catenin signaling pathway, inhibiting tumor growth [75, 76]

Assessments using hyperglycemic glucose clamps and oral glucose tolerance tests

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