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Description
Hyperoxic-hypoxic paradox has been reported in previous therapeutic uses of oxygen and the effect has been extensively discussed in literature ( FIGURE 1 There are a number of different processes that contribute to cellular longevity and the prevention of cell senescence

GSH is the reduced form because its an electron donor

Cells were maintained in Minimal Essential Media (MEM) with Eagle [138] salts (Cellgro, Mediatech, Herndon, VA, USA) with 10% fetal bovine serum, FBS, (Invitrogen, Carlsbad, CA, USA)

10.1016/j.jad.2016.08.011 51

10.1002/bit.27538

101 The in vitro drug release could be evaluated by using dialysis conditions