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In combination with TMZ, DPDS further reinforced these effects, leading to a broader suppression of inflammatory mediators (IL6, IL1B, NFKB1, TNF, and PTGS2) and additional downregulation of oxidative stressrelated genes (NRF2, GPX1, GPX4, SELENOS, KEAP1, SELENOK, SELENOI, and TRXR1) (Figs

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