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Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
Materials and Methods Animal Study New Zealand female white rabbits (12 weeks old, weighing 3.5 0.2 kg, N=40) were obtained from Koatech (Seoul, Korea)
Figure 3 3.5 lipoic acid modulates the balance between the major components of ascorbate-glutathione cycle under Pb stress conditions To investigate the effect of ALA on the cellular redox balance under Pb stress, we measured the major components of the ASA-GSH cycle ( Figures 4AF )
THs trigger biological effects both by directly affecting gene expression through the interaction with nuclear receptors (genomic effects) and by activating protein kinases and/or ion channels (short-term effects)
Ascorbic acid is oxidised to DHA in plants by utilizing sequential electron transmissions with MDHA as an intermediate free radical [191] (Fig
Tiwari M, Lopez-Cruzan M, Morgan WW, Herman B
