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In addition to its role in oxidizing macromolecules such as proteins and lipids, H 2 O 2 has also been proposed to function as a signal to induce the expression of genes involved in the senescence process ( Arabidopsis could be induced by ozone (Miller et al., 1999) and the expression of many other SAGs were also induced by ROS (Navabpour et al., 2003), indicating that ROS might function as a signal to promote senescence

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Endo Y, Stein BES, Potter HG

Proc Natl Acad Sci USA 96:846851 Messina S, Eens M, Casasole G, Ablelgawad H, Asard H, Pinxten R, Costantini D (2017) Experimental inhibition of a key cellular antioxidant affects vocal communication

Because they're patented properties, it's unclear how these branded forms can withstand the digestive environment, but both have demonstrated their potential to do so in clinical studies

1 2 Current Opinion in Clinical Nutrition and Metabolic Care