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doi: 10.1210/me.2009-0402 93 MaseroliEComeglioPCornoCCellaiIFilippiSMelloTet al

Acetyl-carnitine is more easily absorbed from the gut, crosses the blood-brain barrier more readily, and as a bonus supplies acetate, which may boost mitochondrial metabolism both for energy and acetylcholine production

In patients with ME/CFS, research has shown that the Krebs cycle is often impaired, with blockages occurring at specific enzymatic steps

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[DOI] [PubMed] [Google Scholar] 28.Walling B.L