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Genetic defects in the innate immune system (such as loss of NOD2 function) lead to dysregulation of the hosts immune response to the gut microbiota, constituting a key driver of chronic inflammation (99)
H., Ripple, G., Tutsch, K

NO may also react with O 2 to produce peroxynitrite (OONO ) [263,264]
Clinical Advances in Periodontics , 3 (3), 131-137

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