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The answer involves MTHFR mutations

& RELAX-AHF Investigators

doi: 10.1016/j.ekir.2024.04.028 [DOI] [PMC free article] [PubMed] [Google Scholar] 15.Tchang BG, Knight MG, Adelborg K, Clements JN, Iversen AT, Traina A

Design of the DOVE (Determining Effects of Platelet Inhibition on Vaso-Occlusive Events) trial: a global Phase 3 double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of prasugrel in pediatric patients with sickle cell anemia utilizing a dose titration strategy
