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The second part of the aforementioned simplest oxidation-mediated thioldisulfide conversion mechanism is an electrophilicnucleophilic condensation reaction between RSOH and another thiol to give the disulfide (Reaction 4, where RSOH is the electrophile and RSH is the nucleophile)

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doi: 10.1007/s11033-020-05462-y

Effects of astaxanthin on VEGF level and antioxidation in human aqueous humor: Difference by sex