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doi: 10.1186/1475-2891-11-52

Cognitive protection and brain entropy changes from omega-3 polyunsaturated fatty acids supplement in late-life depression: a 52-week randomized controlled trial

These findings highlight the important role of the carnitine pool as a bridge between cellular metabolism and epigenetic regulation and open the possibility of developing novel therapeutic strategies targeting specific metabolic and epigenetic targets

Acetyl-L-carnitine may also affect dopamine and gamma-aminobutyric acid (GABA) levels and activity, and it reduces glutamate concentration in the synapsis, which provides an analgesic effect

10.3390/pharmaceutics13091439 96 LeeK.JeongJ

Endocrinology 160:16451658