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Constipation was assessed by frequency of defecation, response to laxatives and feces forms which were classified according to Bristol stool scale, (type 1 = separate hard lumps) (type 2 = sausage shaped and lumpy) (type3 = sausage shaped with cracks on its surface) (type 4 = sausage or snake with smooth surface) (type 5 = soft blobs) (type 6 = fluffy pieces) (type 7 = entirely liquid) 17

[DOI] [PubMed] [Google Scholar] 72.Worthington, A

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and after applying the inclusion and exclusion criteria (figure 1), 30 of these were rejected because they did not adjust to the topic of our review, 3 of them were reviews, comments, or other document types, and therefore did not meet the inclusion criteria, and another 2 because the study population were not PTNBs (exclusion criteria)