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Chembiochem 2016, 17 (5), 394397

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Compelling evidences in this paper have demonstrated that a wide range of bioactive compounds derived from natural sources activate Nrf2/Keap1 signaling and protect against CVD development

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The finding shifted understanding of how mitochondria communicate beyond energy production, signaling through circulating peptides that reach distant tissues

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Specifically, the system was shown to significantly reduce GFP expression, demonstrating effective RNA-mediated gene silencing in mammalian cells [129]

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