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A recent groundbreaking discovery identified a novel, copper-dependent form of regulated cell deathcuproptosischaracterized by lipoylated protein aggregation and loss of iron-sulfur clusters

Therefore, manipulating the uptake and metabolism of lipids, including glycerophospholipids and cholesterol, may be an effective means of sensitising MM cells to ferroptosis

While levodopa is still considered the gold-standard of symptomatic efficacy, its chronic use is associated with the development of response oscillations and drug-induced dyskinesias in a majority of patients

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