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Kluczowe prace: Pickart (1973, odkrycie z osocza), Pickart & Margolina (zdolno wizania z ponad 4000 sekwencjami genowymi), oraz liczne publikacje w Archives of Biochemistry and Biophysics

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In addition, this route enables the treatment of VB12 deficiency in patients with swallowing disorders or malabsorption syndrome (inflammatory intestinal diseases, intestinal surgery, short bowel syndrome, etc.) 14 , 15

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PCD can be more severe at birth than CF due to the immediate failure of ciliary clearance, and so infants with PCD often present with more respiratory distress and develop bronchiectasis with recurrent infections earlier than those with CF (Mller et al., 2006