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Elevated levels of lipase in your blood can also be a sign of: Pancreas diseases like a blocked duct or pancreatic cancer Chronic kidney disease Peptic ulcer (a sore in your stomach lining) Gallbladder disease Gastroenteritis (inflammation of the stomach caused by a virus) Intestinal problems, like a blocked intestine Problems with your salivary (spit) glands, such as cancer or infections Diabetes Alcohol use disorder Low lipase levels Low lipase levels that are close to 0 could be a sign that the cells in your pancreas are damaged

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