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M.tb utilizes fatty acids for specific purposes, including as substrates for beta-oxidation, acyl primers for polyketide lipid synthesis, or by incorporating them into phospholipids and/or triacylglycerol (TAG) (Lovewell et al., 2016)

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Evidence from cultured cells showed that testosterone induced the levels of Pgc-1 and Tfam genes in C 2 C 12 myogenic cells (83) and increased the number of myotubular and mitochondrial DNA copies in myogenic cells, which was notably attenuated by an inhibitor of AR (84)

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