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We posit that antioxidant functions of parkin may explain many of its previously described, protective effects in vertebrates and invertebrates that are unrelated to E3 ligase activity.

The Q statistic and Eggers test were used to assess heterogeneity and risk of publication bias, respectively

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Glutathione is a potent antioxidant that helps counteract the effects of melanin, the pigment responsible for skin discoloration

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