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It influences gene expression and directly supports mitochondrial function, helping mitochondria produce more ATP while buffering oxidative stress

(2011) The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer

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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Jakoby W.B

Briefly, total RNA from cells was isolated using a Pure link RNA Mini kit (Life Technologies, USA), according to the manufacturers protocols