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5.4 Effects of COVID-19 and CoV-2 S on innate immunity Although viruses usually supress or avoid host immunity, CoV-2 S has been suggested to induce inflammation via a TLR2 (or TLR4) and MyD88-dependent dependent activation of the NF-B pathway in human and mouse macrophages (279), and also to trigger lung cancer progression, again via TLR2 (331)

10.1182/blood-2009-05-224824 323 WangX.ReznickS.LiP.LiangW.van BreemenC

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(2019b) showed that melatonin ameliorates Al-induced root growth reduction by interrupting nitric reductase- and nitric oxide synthase-dependent nitric oxide production which contributes to cell cycle progression and quiescent centre cellular activity