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Transcriptome Changes and Neuronal Degeneration in an In Vitro Model of B Vitamin Depletion

MOTS-c is a short peptide (16 amino acids), which makes it relatively resistant to the enzymatic degradation that degrades larger peptides, but also means that reconstitution technique and storage conditions matter considerably

The rationale for combining them is based on mechanistic complementarity (non-overlapping pathways), individual safety profiles, and clinical observations from practitioners administering the combination

[DOI] [PMC free article] [PubMed] [Google Scholar] 166.Prentice KJ, Saksi J, Hotamisligil GS

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