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Increased free water in the substantia nigra in idiopathic REM sleep behaviour disorder

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However, maleimide conjugates can present stability issues in biological systems, and the activated ester in (Figure d) is rapidly hydrolyzed in alkaline aqueous media, reacting with both thiols and amines

In COPD, endothelial dysfunction occurs in the early stages of the disease and worsens with pulmonary obstruction severity and during acute exacerbations [33]

As a fragment of growth hormone that specifically targets fat metabolism, it appears to avoid many of the side effects associated with full growth hormone therapy, such as joint pain, fluid retention, and effects on glucose metabolism