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Emergency unblinding may only occur on an individual basis for safety reasons if the information can help the treatment of SAEs or SUSARs

DigeZyme digestive enzymes are included to optimise the breakdown and absorption of protein and other nutrients

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This has been supported by the demonstration of a decrease in serum citrulline in these patients [63]

Despite these advances, CAR-M research in AIDs remains largely preclinical, underscoring the need for clinical safety validation, and systemic CAR-M distribution, notably hepatic accumulation, poses risks of off-target toxicity and reduced efficacy (108)

Dysregulation of the MET/HGF pathway leads to uncontrolled cell proliferation and oncogenesis and is observed in multiple tumour types [9]