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15, 16-Dihydrotanshinone I protects against ischemic stroke by inhibiting ferroptosis via the activation of nuclear factor erythroid 2-related factor 2

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increased xanthine oxidase (XO) activity, increased malondialdehyde (MDA) levels, and alterations in antioxidant status, such as low levels of reduced glutathione (GSH) and high levels of glutathione disulphide (GSSG).13,2426 So far, one recently published study has assessed mucosal proliferation, apoptosis and oxidative stress in duodenal biopsies of patients with cirrhosis and found a significantly increased intestinal lipid peroxidation (i.e