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While direct preclinical studies on p38 MAPK inhibition in tinnitus models are not detailed in the provided references, the principle is supported by the broader neuroinflammation literature

Statistical analysis The study results were evaluated using a one-way analysis of variance test

who demonstrated that patients with SSc-ILD who receive both pirfenidone and immunosuppressants have a statistically significant improvement in FVC at 24 weeks compared to patients receiving only immunosuppressants (56)

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Reconstitute only what you can use within the stability window, or plan to aliquot and freeze the excess immediately