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Furthermore, there is already a wealth of evidence to support these targets as interventions to successfully restore cellular NAD+ levels and multiple safe and well-tolerated active ingredients against these targets already exist

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Protocol 1: social anxiety support Goal: Reduce social anxiety before specific events Approach: Form: Intranasal spray Dose: 24 IU (3 sprays per nostril) Timing: 30-45 minutes before event Frequency: As needed, not daily Expected results: Reduced anticipatory anxiety Improved ability to engage in conversation Enhanced reading of social cues Effects lasting through typical social event (1-2 hours) Protocol 2: relationship enhancement Goal: Enhance emotional connection and intimacy Approach: Form: Intranasal spray or sublingual troche Dose: 20-32 IU Timing: 30-50 minutes before quality time with partner Frequency: 2-3 times per week maximum Expected results: Increased feelings of connection Enhanced response to physical touch Improved communication Greater satisfaction with intimate experiences Protocol 3: chronic pain support Goal: Reduce chronic pain through analgesic effects Approach: Form: Subcutaneous injection Starting dose: 20 mcg once daily Titration: Increase by 10 mcg every 3-5 days as tolerated Maintenance: 20-40 mcg once or twice daily Expected results: Reduced pain intensity Improved pain tolerance Secondary mood benefits Better sleep quality Protocol 4: general mood support Goal: Daily mood stability and stress resilience Approach: Form: Intranasal or sublingual Dose: 10-20 IU Timing: Morning or evening, consistent daily Duration: 4-8 week cycles with 1-2 week breaks Expected results: Improved baseline mood Better stress coping Enhanced social interactions Improved sleep quality SeekPeptides members access additional protocols, personalized guidance, and community support for optimizing their peptide research

Vadher K, Patel H, Mody R et al (2022) Efficacy of tirzepatide 5, 10 and 15 mg versus semaglutide 2 mg in patients with type 2 diabetes: an adjusted indirect treatment comparison