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Inside the cells, asparagine is the precursor of aspartate for conversion into malate as a tricarboxylic acid cycle intermediate for respiration or acts as a neuro-transmitter in neuro-endocrine tissues [66]

The DMSO solution of PS-CHO (5 mg, 1 mL) was slowly added into 19 mL ddH 2 O containing 1 mg of DSPE-PEG2000-HA or DSPE-PEG2000, and this solution was mixed under sufficient stirring

Some modified peptides can be administered nasally or dermally (via cream), but bioavailability through these routes remains inconsistent and rare

doi: 10.1016/j.cmet.2021.12.005 181

NOMEs also have antiproliferative effects linked to nitroalkylation of RAD51 recombinase, a critical component in the DNA repair machinery

A discussion of major and secondary ROS and RNS follows
