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In addition, our data provide evidence that the protective effects are likely related to modulation of the NF-B and Nrf2/Keap1 pathways

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Selenium was found to play a role in thyroid function and it is postulated that the link is through a specific enzyme called type-1 5-deiodinase, which is involved in the conversion of thyroid hormones, which contains selenium [23]

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Studies have indicated that luteinizing hormone (LH) levels and LH receptor expression increase in premenopausal patients with FPHL