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BM biopsy revealed hypercellular marrow with erythroid hyperplasia and no significant dysplasia or increase in blasts along with a DNMT3A missense mutation of unknown significance on myelodysplastic syndrome panel testing

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Receptor activation initiates intracellular pathways including PI3K/Akt and MAPK signalling cascades, which regulate cellular proliferation, protein synthesis, metabolic activity, and apoptosis resistance

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