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Attempts with compounds lacking this moiety have been made, but these compounds are not better than oxime-based reactivators regarding efficacy against OP compounds (for review see [118]

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3.7 Fragile X-associated tremor/ataxia syndrome Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS), typically caused by a premutation in the FMR1 (fragile X messenger ribonucleoprotein 1) gene, is a nervous system disorder in older adults characterized by tremors, ataxia, memory issues, and mood disorders

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