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Mice with claudin-2 or claudin-15 deficiencies in the small intestine reveal that these transmembrane proteins play essential roles in the transepithelial paracellular channel-like permselectivity for extracellular monovalent cations, especially Na(+), in both infants and adults [13]

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van der Voort R, Taher TE, Wielenga VJ, Spaargaren M, Prevo R, Smit L, David G, Hartmann G, Gherardi E, Pals ST