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Niethammer P, Grabher C, Look AT, Mitchison TJ (2009) A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

For example, bone marrow mesenchymal stem cell-derived exosomal miR-425-5p inhibited the proliferation, apoptosis, invasion, and migration of acute myeloid leukemia cells by targeting Wilms tumor 1-associated protein (WTAP) [87]

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In the last years, several studies have reported new information on the role of a class of non-coding RNAs on the production and fertilizing potential of sperm [131]

On the other hand, the inhibition of Nrf2 signaling might be employed to enhance the sensitization of chemoresistant tumors to cytotoxic agents, and in this context, it has recently been reported that brusatol, a compound found in a plant extract, acts as inhibitor of this pathway and may exhibit therapeutic utility [111]