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This exclusion is significant considering that patients with obesity have a higher risk of developing depression 24

Kurian, who is also the immediate past president of the American Society for Metabolic and Bariatric Surgery

Interestingly, weight loss was minimal during the trial, indicating the improvement wasn't simply due to shedding pounds

Circulating plasma GLP-1 levels rise from approximately 510 pmol/L in the fasted state to 1550 pmol/L in the postprandial state, with peak levels depending on meal composition, caloric density, and rate of gastric emptying

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GLP-1 receptor agonists routinely produce 1520% weight loss in clinical trials, rivaling results previously seen only with bariatric surgery