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Currently, clinical trials are investigating efficacy of CB-839 treatment in AML (NCT02071927) ( 5 Conclusions Considering our results and those of previous studies, we suggest that CLL cells can efficiently rewire their amino-acid and glucose metabolism to evade glutaminase inhibition

Several biological studies in vitro have demonstrated the antiparasitic activity of THTT, which is related to a non-specific high cytotoxicity [12, 13]

Bcuwe P, Slomianny C, Camus D, et al

This finding suggests that dopaminergic strategies could act on this mechanism and play roles in the antidepressant response, and drugs that modify the inflammasome could also be considered as novel therapeutic agents for depression

This series is my effort to demystify the peptide landscape, grounded in evidence and clinical caution

For those battling dark circles, fine lines, and the telltale signs of fatigue, the battle for a bright, refreshed gaze can be an unending quest