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Epidemiological studies suggest maternal immune activation (MIA), especially during the second trimester increases the risk for developing ASD [3]

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PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percreta

This is accompanied by the breakdown and fragmentation of myelin, which is initially cleared by Schwann cells and later, to a more substantial degree, by macrophages [7]