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(Source 13) Methylcobalamin Methylcobalamin, or methyl B12, is the second active coenzyme form of vitamin B12 and is bioidentical as a supplement

Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

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[2] [16] Dietary deficiency without neurological features: Initial loading doses followed by maintenance therapy, with consideration of oral supplementation in appropriate cases

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