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During the age of precision-therapeutic medicine, investigating the link between irregularities in the HGF/c-MET signaling pathway and cancer treatment is crucial

The damaging effects of Nrf2 modification in the lung, as an example, may increase the susceptibility of the affected tissues to the oxidative stress of the oxygen environment, as well as compromise the function of epithelial cells and phagocytes, such as granulocytic leukocytes and monocytes/macrophages [49,50]

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Role of ROS and nutritional antioxidants in human diseases

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M.DAlcamoM.GoffinV.CrostaL.et al (2003)