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In a previous study, we have reported that KEAP1 mutant tumors respond to CB-839 treatment, while growth of wild type tumors is unaffected in vivo (Romero et al., 2017)

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Illouz F, Braun D, Briet C, Schweizer U, Rodien P

It influences adjacent vascular smooth muscle cells (VSMC) through several mechanisms

1 2 3 4 Clinical pathology

America the Strong: Conservative Ideas to Spark the Next Generation
