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4.9 Effects on general anaesthesia One of the major concerning side effects of GLP-1RA use in anesthesia are the complications of the GI tract presenting as delayed gastric emptying and elevated gastric residual content along with other symptoms (nausea, vomiting, abdominal distension and dyspepsia) (106)

Besides the complex pharmacological interplay between the GIP receptor targeting ligands and the receptor addressed above, another aspect of GIP biology is the tissue-specific actions, which might affect the clinical results of GIP targeting treatments

To view a copy of this licence, visit About this article Cite this article Chen, H., Liu, S., Gao, S

Breastfeeding parents need an average of at least 500 additional calories daily, and GLP-1s can significantly decrease appetite and compromise energy and nutrition

Importantly, circulating DPP4 is augmented in obese and type 2 diabetic subjects, and it may represent a molecular link between obesity and vascular dysfunction

These changes synergize with the GLP-1s effects for instance, as the medication curbs appetite, coaches help patients to leverage that effect by establishing a more balanced meal pattern, so they can nourish their bodies adequately while still maintaining a calorie deficit