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RESULTS LDHB regulates glutathione metabolism in KRAS -dependent lung cancer cells To identify metabolic pathways that underpin the function of LDHB in KRAS -dependent lung cancer [27, 28], we performed unbiased metabolomics of LUAD cells carrying KRAS mutations (A549, H358)

Wouters, E

PLoS One 9

We find that loss of Lkb1 activity renders cells dependent on glutamine for their growth

10.1186/s13024-017-0186-8 24 DuttaS.HornungS.KruayatideeA.MainaK
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