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This decrease in enzyme activity can lead to a buildup of a substance called homocysteine in the blood, which is associated with an increased risk of cardiovascular disease, stroke, and other health problems

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To avoid the deleterious effects of high doses of therapeutic drugs on macrophages, drugs can be loaded into liposomes or nanoparticles to enhance their stability, and DOX-loaded PLGA nanoparticles [72] and 7-ethyl-10-hydroxycamptothecin (SN38) nanoparticles [73] delivered by macrophages have shown good antitumor effects

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At the Centeno-Schultz Clinic, board-certified, fellowship-trained physicians will review history, medications, and current imaging, along with a detailed physical examination and an ultrasound examination