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Angiogenesis, or new blood vessel formation, has been consistently observed in animal models, which improves nutrient delivery and accelerates healing in injured tissues

doi: 10.1152/jn.00207.2001

Some individuals notice changes in 34 weeks, while others require longer depending on baseline metabolic health
"Conclusions of a WHO Technical Consultation on folate and vitamin B12 deficiencies"

Even partial freezing at the edges of a vial can cause localized damage

Why Vegans are at Risk of Vitamin B12 Deficiency
