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doi: 10.1016/j.biomaterials.2021.120944, PMID: [DOI] [PubMed] [Google Scholar] 87

HFpEF and DM share common pathophysiological mechanisms, including systemic inflammation, myocardial fibrosis, endothelial dysfunction, and insulin resistance [3]

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A 2020 study in an animal model of RLS showed that the H3 receptor in the striatum is likely involved in limb movement during sleep