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Huang et al., 2024)
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The transporter, OCTN2, is located in the apical membrane of the renal tubular cells, where it plays a role in tubular reabsorption
Estrogen-Containing Hormonal Contraceptives Estrogen-containing hormonal contraceptives may increase the clearance of valproate, which may result in decreased concentration of valproate and potentially increased seizure frequency
To screen the differential metabolites (CARs), principal component analysis (PCA) and partial least squares discriminant analysis (OPLS-DA) were conducted by using SIMCA-P 17.0 software (Umetrics AB, Umea, Sweden)
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