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A large, population-based retrospective cohort study was conducted using the TriNetX platform, which provided real-time access to electronic health records of 634,265 adult patients with MASLD/MASH
Lipid Profile Improvements Treatment with retatrutide resulted in favorable changes to lipid profiles: Reduced triglycerides, with bias toward reduction in short-chain and saturated species Decreased LDL and VLDL cholesterol Improved markers associated with enhanced insulin sensitivity and reduced systemic inflammation[3] These changes in lipid metabolism may contribute to retatrutide's cardiometabolic benefits and warrant further investigation for potential cardiovascular outcome benefits
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