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Carcinogenesis 28:23632366 Nagayoshi H, Matsumoto A, Nishi R, Kawamoto T, Ichiba M et al (2009) Increased formation of gastric N(2)-ethylidene-2-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanol

NO is a multifunctional signaling molecule, intricately involved with maintaining a host of physiological processes including, but not limited to, host defense, neuronal communication and the regulation of vascular tone

C.Ikeda-SaitoM.IsayaG.SzwedaL

While glutathione is not a medical treatment for re-pigmentation, it is a key antioxidant that helps protect pigment-producing cells from oxidative damage

DNA Fragmentation DNA fragmentation results from increased oxidative stress and consequently leads to an increase in ROS that can oversaturate the sperm cells few antioxidant defense mechanisms and increase oxidative stress, which further directly damages DNA [45]

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