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Pharmacol Rev 65:223254 Allouche S, Noble F, Marie N (2014) Opioid receptor desensitization: mechanisms and its link to tolerance

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The study experiments were performed in accordance with relevant guidelines and regulations and approved by the local Ethical Committee Guidelines for the care and use of laboratory animals of Faculty of Medicine of SfaxUniversity of Sfax (12/ES/15_2022)

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A study examined the impact of NAC (1,800 mg/day for 4 weeks) on cerebral GSH and clinical symptoms in 16 ME/CFS patients