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These include preferential distribution and retention within specific tissues, the biological activity of secondary metabolites, and synergistic interactions across various pharmacological targets [51]

J Chongqing Med Univ

Important mediators of the adaptive responses are the adenosine monophosphate-activated protein kinase (AMPK), the transcription factors NF-B, together with p38 MAPK, and members of the FoxO transcription factor family [91,92,93]

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At its core, kojic acid soap is a fusion of the skin-lightening compound, kojic acid, with cleansing agents