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Its neurogenic effects may aid in slowing the progression of these conditions, providing valuable support for brain health

10.1038/s41564-023-01560-2 26 MaQ

Immune Signaling and the ENS TLRs and other components of the innate immune system (e.g., macrophages) may serve as sensors of gut microbial presence and deliver messages to the ENS that result in changes in gut nervous system development and function

Mast cell stabilisers, including cromolyn and more recently developed synthetic compounds, are used in clinical settings to control allergic responses 56 which are highly reliant on mast cell degranulation and activation

Additionally, the bidirectional relation between neuroinflammation and neuronal injury requires further investigation

DRP1 has been reported to play a central role in the pro-inflammatory macrophage response
